Ghoul Problem Quests

The quest walkthrough below is an example of one of the many "Ghoul Problem" quests you'll get from random settlers in one of your random workshops or settlements. The objective is simply talking to the marked settler to start the quest, heading to the marked location and killing a significant number of ghouls. Usually, you don't need to kill all ghouls as the quest will eventually point you to the location of the ghouls needed to be killed in order to complete the mission.

Once you cleared the mission area, return to the settler who gave you the mission and talk to him/her to complete it. If ever the settler who gave you the mission is a provisioner or someone you assigned to establish Supply Lines, you have to wait for that NPC to arrive in one of the settlements he/she'll visit.

Tenpines Bluff will be marked in your map a short distance to the east from Sanctuary. Upon reaching the area, talk to the one of the two settlers there to update your quest. Next, you'll have to go to College Square.

When you fast travel to the location, you'll be taken to an overrun checkpoint. There are mines on the street as well so use your VATS to target them if you can't see them immediately. You can take out multiple ghouls by blowing up the car wreck there. Take out the ghouls and continue following the marker. You'll have to enter the closed-area College Square Station. Just clear out the place of ghouls in the immediate area and your quest will update. For notable loots, just follow this guide's location page of the area.

The train station itself isn't large, filled with ghouls, and there are some good loot inside. Your target is the Feral Ghoul Stalker in the maintenance room of the western wing so be prepared. Make sure to also find the College Station Key on top of the tables there. You can use that key to open the ticket booth in the area. Once you're done looting the area, return to the settlers in Tenpines Bluff to report your success. After that, talk to Preston Garvey to complete the quest.

Completing this quest will unlock more quests (Raider Troubles at Nordhagen Beach, Taking Independence). You can also now use Tenpines Bluff as your new workshop.