Nico is an associate of Nero's branch of the Devil May Cry business. Her full name is Nicoletta Goldstein but she is better known as Nico. She is an expert weapon craftswoman and engineer and is the creator of the various cybernetic prosthetics Nero wields to hunt demons.
In Devil May Cry 5 you can visit Nico's shop which is a van to purchase upgrades to the Devil Breaker as well as other weapons. By spending Red Orbs, you will be able to create different cartridges for the Devil Breaker, which are used to change its abilities. Blue Orbs can also be bought in Nico's Shop using the Red Orbs you earn.
At her shop in the van Nico sells 6 Blue Orbs (not fragments), the price of which increases exponentially and buying all 6 from Nico will cost you 78,000 Red Orbs.
• Blue Orb 1:
Cost 1,500 Red Orbs
• Blue Orb 2:
Cost 3,500 Red Orbs
• Blue Orb 3:
Cost 6,000 Red Orbs
• Blue Orb 4:
Cost 9,000 Red Orbs
• Blue Orb 5:
Cost 18,000 Red Orbs
• Blue Orb 6:
Cost 40,000 Red Orbs
Check out our All Collectible Locations page to learn the whereabouts of all the Blue Orbes in Devil May Cry 5.